Cytokinetics

Principal Scientist, Computational Chemistry

South San Francisco, California, USA · Principal

Sponsorship not specified$203k-$236kDetected 62 days ago

PythonAlgorithmsMachine LearningData AnalysisComplianceResearchLeadershipCommunicationCollaborationMentoring

About the role

The candidate will play a key role in advancing discovery programs by serving as an active member of project teams.
The base pay actually offered will take into account internal equity and also may vary depending on the candidate's geographic region, job-related knowledge, skills, and experience among other factors.

As the lead Computational Chemist on our programs, you will utilize your experience in structure-based and ligand-based design and modeling to drive new discovery processes.
Lead efforts focused on molecular modeling, structure-based drug design and generative design
Advance current drug discovery process by co-developing augmented computational strategy for hit-finding through lead optimization
Foster an environment of innovation and entrepreneurship to build, integrate and apply computational tools and workflows
Provide hands-on computational chemistry guidance and support for drug discovery projects
Guide innovation around small molecule computational design and optimization
Establish the Computational Chemistry strategy, including leveraging CROs and collaborators to drive our pipeline efficiently and effectively
Capable of providing hands-on computational chemistry and modeling support for drug discovery projects with strong skills leveraging state-of-the-art software and approaches (e.g. MOE, Schrodinger tools, cloud computing, FEP and AlphaFold2)

12+ years of experience in the biotech or pharmaceutical industry and demonstrated impact on project progression
Proven leadership experience in driving teams towards common scientific goals and leading scientific drug discovery-focused activities

Emphasis will be placed on utilization of technologies and processes to improve quality of our compounds as they move towards the clinic.

In the U.S., the hiring pay range for fully qualified candidates is $202,500-$236,250 per year.
The base pay actually offered will take into account internal equity and also may vary depending on the candidate's geographic region, job-related knowledge, skills, and experience among other factors.

This includes enhancing and complementing our hit-to-lead and lead optimization processes utilizing emerging technologies (e.g. active learning).

Collaborate closely with Research departments, especially Medicinal Chemistry, Discovery Biology, and Discovery Technologies as an integral part of our compound design team

This listing is sourced directly from Cytokinetics's careers page and normalized into a canonical job model.