Korro Bio

Associate Director / Director, Toxicology

60 First St, Cambridge, MA 02141 · Director

Sponsorship not specified$175k-$260kDetected 63 days ago

Product ManagementPharmacologyLeadershipCommunicationCollaborationPublic SpeakingOrganizational Skills

About the role

By editing RNA instead of DNA, Korro is expanding the reach of genetic medicines by delivering additional precision and tunability, which has the potential for increased specificity and improved long-term tolerability.
Korro is based in Cambridge, Massachusetts.
They are reinforced daily and serve as key dimensions in the hiring process to help us ensure that Korro is a magnet for outstanding talent and a great place to work.

Lead the design, execution, and interpretation of GLP and non-GLP toxicology studies to support target assessment, platform innovation initiatives, development candidate selection and regulatory submissions.
Develop and implement nonclinical safety strategies specific to oligonucleotide therapeutics, including considerations for sequence, chemistry, delivery, and off-target effects.
Mentor and develop junior scientists and contribute to a culture of scientific rigor, collaboration, and innovation.
Korro is a biopharmaceutical company focused on developing a new class of genetic medicines for both rare and highly prevalent diseases using its proprietary RNA editing platform.
Korro is generating a portfolio of differentiated programs that are designed to harness the body's natural RNA editing process to effect a precise yet transient single base edit.
Korro Bio is seeking a highly motivated Associate Director or Director of Toxicology to lead the design and execution of nonclinical safety studies across our RNA editing portfolio.

6-10+ years of relevant industry experience in toxicology, with a strong track record of supporting mechanistic toxicology and IND-enabling programs.
Deep knowledge of global regulatory expectations, ICH guidelines, and GLP principles.
Strong leadership, communication, and organizational skills, with the ability to work effectively in a fast-paced, matrixed environment.
Proven ability to influence across functions and effectively interface both internal and external stakeholders.
Contribute to regulatory strategy and agency interactions, with experience with accelerated development pathways and/or rare disease programs being highly desirable.

Hands-on experience with oligonucleotide-based therapeutics is a plus.
Mandarin language proficiency is a plus, particularly for candidates with experience collaborating with China based CROs
Familiarity with GalNAc or other delivery systems is a plus.
prior experience working with CROs in China (or broader APAC region) is highly desirable.
Mandarin language skills are a plus, particularly for candidates with experience working with China based CROs.
Experience designing, outsourcing, and overseeing nonclinical toxicology studies at external CROs, including international vendors
board certification (e.g., DABT) strongly preferred.
PhD, DVM, or equivalent in toxicology, pharmacology, or related field

Benefits: Korro offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance, a dependent care flexible spending acc

We are building a company with extraordinary people with an audacious vision to create transformative genetic medicines for prevalent diseases.
Join us as we redefine what's possible in genetic medicine and work to make a lasting impact on human health.
Prepare and review regulatory documentation, including INDs, CTAs, Investigator's Brochures, and responses to health authority queries.

We are collaborative and united by a common mission.
Our values - Rewrite the future, On the Cutting Edge, Better Together, Dynamically Different, Kindness and Integrity form the fabric of the organization.

This listing is sourced directly from Korro Bio's careers page and normalized into a canonical job model.