DNAstack

DNAstack

Bioinformatics Analyst

Toronto, Ontario, Canada · Senior · Full-time

Work authorization required$100k-$150kDetected 33 days ago
PythonJavaBashSQLAWSGCPAzureDockerData AnalysisAccessibilityProduct ManagementProject ManagementBioinformaticsNGSResearchLab ResearchCommunicationCollaborationCritical ThinkingBiostatistics

About the role

  • We're looking for an experienced Bioinformatics Analyst to join our bioinformatics team on a full-time, 12-month contract.
  • You will use standardized and best-in-class technologies and write clear documentation to ensure that your work can be reused and built upon by the community.
  • Projects span a wide range of disease areas and data modalities, including multi-omics integration, spatial and single-cell transcriptomics, and cross-cohort analysis on federated cloud research platforms.

Responsibilities

  • Work with the team to develop and optimize reproducible, scalable, and well-documented pipelines using WDL, Docker, and cloud-based infrastructure (e.g. GCP, AWS, Azure)
  • Collaborate with partners in academia and industry to develop pipelines to process and harmonize a variety of genomics datasets
  • Evaluate, compare, and validate analysis methods using best-in-class tools (e.g., GATK, bcftools, samtools, VEP, etc.)
  • Support workflows handling a variety of -omics data types (e.g., WGS, WES, RNA-seq, methylation, tumour/normal, proteomics, etc.)
  • 5+ years of hands-on experience building and running NGS analysis pipelines
  • At DNAstack, we are committed to building and fostering an inclusive, accessible environment for everyone.

Requirements

  • Master's degree in bioinformatics, computational biology, biostatistics, or equivalent industry experience
  • Ability to work in a fast-paced startup environment with a bias toward action, a willingness to learn new things, and a pragmatic approach to tradeoffs.
  • Experience with workflow languages like WDL, CWL, Nextflow, or Snakemake
  • A background in biology/genetics with proven critical thinking and research skills
  • Experience with single-cell or single-nucleus RNA-seq analysis
  • Familiarity with spatial transcriptomics platforms and common single-cell data formats

Nice to have

  • Experience with clinical genomics, ACMG variant interpretation, or diagnostic pipelines
  • Statistical and visualization skills for exploring -omics datasets
  • Familiarity with public datasets (e.g., gnomAD, TCGA, ENCODE) and FAIR data principles
  • Experience working with biological databases or data integration projects.
  • Experience with cloud computing (GCP, AWS, or Azure) or HPC environments
  • Experience with spatial deconvolution or multi-modal single-cell integration methods
  • Background in a disease area relevant to genomic medicine (e.g., neurodegeneration, oncology, rare disease)
  • Experience with cloud-based research analysis platforms or federated data access workflows

Skills

  • Your work will directly influence tools used by national and international genomics networks.

Compensation

  • The salary range for this role is $100,000 to $150,000.

Benefits

  • Comprehensive health benefits: medical, dental and vision coverage for you and your dependents
  • Three weeks vacation
  • Maternity and parental leave top-up programs
  • Career development and learning support
  • Opportunity to participate in DNAstack's Employee Stock Option Program
  • We regularly review our compensation practices to identify and address any pay equity gaps.
  • Pay equity is an ongoing process, and we are committed to maintaining compliance with legislative requirements while fostering a workplace that values fairness, respect, and inclusion.
  • Remote friendly, with flexible hours and the opportunity to work on-site at our Toronto office
  • One-time remote office set-up stipend

Company info

  • Enjoy a flexible, remote-friendly team culture along with a competitive salary, benefits, and employee stock option program.
  • Where You'll Work
  • This role offers the flexibility of remote work, with the option to work in person from our Toronto office.
  • This arrangement supports your needs and promotes a healthy work-life balance.
  • To be considered for this position, you must be eligible to work in Canada.
  • this posting is for an existing vacancy that we are seeking to fill.
  • For compliance reasons, all offers of employment at DNAstack are conditional upon a successful background check that may consist of prior employment verification, reference checks, education confirmation, criminal background, or other information, as permitted by law.
  • Analyze customer technical needs to provide tailored recommendations for pipeline implementation, and train customers and partners on how to best utilize our platforms
  • What We're Looking For
  • At DNAstack, we are dedicated to providing pay transparency to all candidates.

This listing is sourced directly from DNAstack's careers page and normalized into a canonical job model.