Arc Institute

Arc Institute

Senior Research Associate, Neural Cell Production (Fixed-Term Contract)

Palo Alto, CA · Senior · Contract

H1B sponsorship available$84k-$114kDetected 22 days ago
Full-Stack DevelopmentCadenceBioinformaticsFlow CytometryCell CultureResearchCollaboration

About the role

  • About Arc Institute Arc Institute is an independent nonprofit research organization at the interface of artificial intelligence and biology, working to accelerate scientific progress and understand the root causes of complex diseases.
  • Arc's Technology Centers and Core Investigator labs work side by side, integrating experimental and computational biology under one roof to tackle problems neither could solve alone.
  • More than 300 Arconauts work together at our Palo Alto headquarters, backed by substantial long-term philanthropic funding.

Responsibilities

  • Join Arc's Alzheimer's Disease Initiative as the production engine behind a first-of-its-kind 3D brain-model screening program, where the cells you make drive disease-target discovery.
  • You will work in close collaboration with the scientists and research associates leading each production workflow to deliver the cells our high-cadence screening calendar depends on.
  • Create banks of QC'd cells and manage their proper registration and documentation in Benchling.
  • Maintain iPSC and progenitor cultures (feeding, passaging, expansion, cryopreservation, thawing) and coordinate production timing against the screening calendar.
  • Follow and help maintain established protocols and SOPs, flagging issues to the workflow leads.

Requirements

  • BS degree in relevant field with 4+ years of relevant experience, or MS degree in relevant field with 2+ years of relevant postgraduate experience
  • Demonstrated ability to execute multiple cell culture protocols with precision and to transition between them accurately, maintaining fidelity to each protocol's specific requirements (workflow, media, and timeline).
  • Experience QCing cells using cellular and/or molecular assays such as flow cytometry, DNA proliferation, or MEAs (experience with one or more of these
  • not all required).
  • Experience with cryopreservation, thawing, expansion, and cell banking.
  • comfort working to a production schedule, and basic data tracking and analysis.
  • Occasional weekend work may be required.
  • Collaborate closely with the team members leading each production workflow to deliver the cell production required to support the screens.

Nice to have

  • Background in an industry iPSC production setting (e.g., cell-products manufacturer, CDMO, or organoid/drug-discovery production group).
  • Experience producing 3D brain organoids.
  • Familiarity with Benchling or comparable ELN systems.
  • You bring strong process discipline and a track record of reproducible production, ideally from an industry or other high-consistency cell production setting.

Compensation

  • The base salary range for this position is $84,250 to $114,250.

Company info

  • About Arc Institute
  • Arc Institute is an independent nonprofit research organization at the interface of artificial intelligence and biology, working to accelerate scientific progress and understand the root causes of complex diseases.
  • Founded in 2021 and based in Palo Alto, Arc partners with Stanford University, UC Berkeley, and UC San Francisco.
  • Unlike academia, our scientists have long-term funding and industry-like resources.
  • Unlike industry, they're free to pursue high-risk, long-term research without commercial pressures.

Visa & Work Authorization

  • This role is not eligible for visa sponsorship.
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