Output
Member of the Technical Staff, Cheminformatics
New York HQ 🗽 · Staff+
Sponsorship not specifiedDetected 46 days ago
PythonMachine LearningLLMsResearchLeadership
About the role
- Output has built a biological reasoning model that understands biology at the scale and complexity life actually operates.
- Our model independently learned the principles of molecular interactions, opening up drug treatments that were previously impossible.
- We're already generating therapies that traditional approaches cannot reach.
Responsibilities
- The hardest problems in both AI and biology are being solved here, and there is room for you to own one.
- This role continues to build the models and computational methods that optimize Output's molecular generation for practical chemistry.
- You will build and maintain cheminformatics pipelines for molecular analysis, property calculation, and candidate assessment
- Healthy feedback focused environment to help you strive - leadership will have high expectations, regularly share constructive feedback, support you and help you grow, and welcome receiving feedback and ideas from you
- You own your day-to-day management.
- You have strong programming skills in Python, with experience building computational pipelines for molecular analysis
- You have drug discovery experience, particularly in hit-to-lead or lead optimization
Requirements
- You will work with the drug discovery and model teams, bringing chemistry expertise to molecular evaluation and candidate prioritization
- You have deep understanding of organic chemistry, synthetic routes, and chemical reactions
- You have experience with retrosynthetic analysis or computational synthesis planning
- You have experience with molecular property prediction or QSAR modeling
- You have publications at top-tier venues (e.g., NeurIPS, ICML, ICLR) or relevant chemistry and cheminformatics journals
- You have experience evaluating or working with generative molecular models
Compensation
- Competitive salary and equity in a growing, well-funded startup
Benefits
- Competitive salary and equity in a growing, well-funded startup
- Excellent medical, dental, and vision coverage
- You have experience training machine learning models on molecular and chemical data, including generative models for chemistry applications
- You are comfortable working at the boundary of chemistry and machine learning, translating constraints and insights between the two
Company info
- We foster a culture of ownership.
- We are assembling a team of individuals who are passionate and take pride in their contributions.
- We value practicality and results-oriented thinking.
- We are committed to making a tangible impact on the lives of patients and the broader community.
This listing is sourced directly from Output's careers page and normalized into a canonical job model.