Twist Bioscience

Twist Bioscience

Sr Research Associate, Upstream in vivo Antibody Discovery

USA - Quincy, MA · Senior

Sponsorship not specified$95k-$113kDetected 40 days ago
Data AnalysisProject ManagementBioinformaticsCell CultureResearchLab ResearchMass SpectrometryProtein AnalysisAnimal StudiesCommunicationCollaborationProblem Solving

About the role

  • About Twist Bioscience Twist Bioscience synthesizes genes from scratch, known as "writing" DNA.

Responsibilities

  • As a member of the Upstream Antibody Discovery team, you will perform wet-lab benchwork including mammalian cell culture, hybridoma fusions, and Beacon-based single B cell screening, including reagent preparation and QC.
  • Record and communicate experimental details, draft reports, and deliver data with a high level of integrity and ethics

Requirements

  • BS in a life sciences or technical field with 5+ years of experience, or an MS with 3+ years of experience in antibody discovery workflows.
  • Strong foundational knowledge of in vivo immunization concepts, hybridoma fusions/culture, and single B cell screening techniques.
  • Demonstrated ability to accurately analyze complex scientific data, troubleshoot processes under tight timelines, and autonomously prioritize tasks across concurrent projects.
  • Direct, hands-on experience with Beacon single B cell techniques.
  • Familiarity with downstream characterization tools, including Carterra SPR, Octet BLI, and developability assays (HPLC and high-throughput plate-based formats).
  • Experience with ELISA, SDS-PAGE, protein quantification, and endotoxin assays.
  • Core Scientific Expertise (Required):

Nice to have

  • Highly Preferred skills:

Skills

  • Single B Cell Platforms: Direct, hands-on experience with Beacon single B cell techniques.
  • Standard Assays: Experience with ELISA, SDS-PAGE, protein quantification, and endotoxin assays.
  • Automation: Experience or interest assisting with laboratory automation integration to boost department capacity and efficiency.
  • About Twist Bioscience
  • Twist Bioscience synthesizes genes from scratch, known as "writing" DNA.
  • Just as children learn to both read and write, the next phase of development for the genomics revolution is the ability to write DNA.
  • Twist Bioscience Corporation is an Equal Opportunity Employer.
  • Compensation may be different in other locations.
  • Massachusetts Pay Range
  • $94,943 - $113,000 USD

Compensation

  • Massachusetts Pay Range
  • $94,943 - $113,000 USD

Benefits

  • In fields such as health care, agriculture, industrial chemicals and data storage, our unique silicon-based DNA Synthesis Platform provides precision at a scale that is otherwise unavailable to our customers.
  • In addition to base salary, this role is eligible for bonus, equity, and a generous benefits package.
  • Education & Experience:
  • Educational Background: BS in a life sciences or technical field with 5+ years of experience, or an MS with 3+ years of experience in antibody discovery workflows.

Company info

  • Strong focus on problem-solving, attention to detail, and a commitment to maintaining data integrity and ethics in a collaborative team setting.
  • At Twist Bioscience, we work in service of people who are changing the world for the better.

Equal opportunity

  • Equal Opportunity Employer.
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