Arc Institute
Senior Research Associate, HPC Production (Fixed-Term Contract)
Palo Alto, CA · Senior
H1B sponsorship available$84k-$114kDetected 19 days ago
Full-Stack DevelopmentOperations ManagementProcess ImprovementBioinformaticsqPCRFlow CytometryCell CultureResearchCommunication
About the role
- About Arc Institute Arc Institute is an independent nonprofit research organization at the interface of artificial intelligence and biology, working to accelerate scientific progress and understand the root causes of complex diseases.
- Arc's Technology Centers and Core Investigator labs work side by side, integrating experimental and computational biology under one roof to tackle problems neither could solve alone.
- More than 300 Arconauts work together at our Palo Alto headquarters, backed by substantial long-term philanthropic funding.
Responsibilities
- Perform quality control (QC) assessments for each lot, which may involve flow cytometry, molecular, and functional assays, and ensure that delivered cells meet defined acceptance criteria defined by the requesting teams.
- Perform troubleshooting on failed productions, escalate and reschedule as needed to maintain supply continuity.
- Maintain rigorous, organized documentation of production runs, QC outcomes, and cell distribution in our ELN/LIMS systems.
- Maintain inventory of key reagents, media, and consumables to ensure uninterrupted production, including proactive procurements.
Requirements
- Proficiency in mammalian cell culture procedures and associated aseptic techniques, including direct hands-on experience with human stem cell (hESC/iPSC) maintenance and HPC differentiation at scale.
- Demonstrated ability to execute reproducible, multi-step differentiation protocols consistently across repeated rounds.
- Experience performing and documenting QC assessments, which include flow cytometry, RT-qPCR, and colony-formation assays.
- Attention to detail and a track record of delivering high-quality work consistently.
- Excellent communication skills and the ability to coordinate effectively across teams.
Nice to have
- Prior experience independently optimizing processes and workflows to improve cell yield and quality.
- Hands-on experience with multiple differentiation protocols.
- Experience working with stem cells of diverse genetic backgrounds (e.g., patient-derived iPSCs).
- Familiarity with reagent inventory, operations management and LIMS platform (e.g., Benchling).
- BS/MS degree in cell biology or related field with 4+/2+ years of relevant work experience.
- Industry or core-facility experience in cell production is strongly preferred.
Compensation
- The base salary range for this position is $84,250 to $114,250.
Benefits
- Execute staggered weekly rounds of hematopoietic progenitor cell (HPC) production and banking with different human stem cell lines (e.g., parental and genetically edited) to support downstream research teams.
Company info
- About Arc Institute
- Arc Institute is an independent nonprofit research organization at the interface of artificial intelligence and biology, working to accelerate scientific progress and understand the root causes of complex diseases.
- Founded in 2021 and based in Palo Alto, Arc partners with Stanford University, UC Berkeley, and UC San Francisco.
- Unlike academia, our scientists have long-term funding and industry-like resources.
- Unlike industry, they're free to pursue high-risk, long-term research without commercial pressures.
Visa & Work Authorization
- This role is not eligible for visa sponsorship.
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This listing is sourced directly from Arc Institute's careers page and normalized into a canonical job model.