Seaport Therapeutics

Senior Scientist, Bioanalytical Science

Boston, MA · Senior

Sponsorship not specified$133k-$157kDetected 27 days ago

RecruitingIntellectual PropertyFDA RegulatoryResearchMass SpectrometryAnimal StudiesLeadershipCommunicationCollaboration

About the role

Seaport Therapeutics is a clinical-stage therapeutics company advancing the development of novel neuropsychiatric medicines in areas of high unmet patient needs.
Seaport is led by an experienced team that invented and advanced important neuropsychiatric medicines and are guided by an extensive network of renowned scientists, clinicians and key opinion leaders.
For more information, please visit www.seaporttx.com.

Support the development and optimization of bioanalytical methods (e.g. LC/MS) to evaluate concentration of API, metabolites, and related species across multiple small and large animal species
Manage execution of method development and sample analysis across multiple external CROs and collaborators
Assist in design and selection of methods of sample extraction and analysis across a range of matrices including lymph, plasma, and solid tissues
Perform pharmacokinetic analysis of data, communicate results, provide scientific interpretations and recommendations to cross-functional project teams and leadership
Manage day-to-day research activities with increasing independence while ensuring alignment with departmental and company priorities

MS/PhD degree in analytical chemistry, bioanalytical chemistry, pharmaceutical analysis with 3+ years for PhD, or 8+ years for MS.
Experience with CROs and managing outsourced studies critical
Ability to adjust rapidly to changing scientific priorities and technologies
Track record of supporting the development and validation of bioanalytical LC-MS/MS methods designed at standards ranging from "fit-for-purpose" through GLP.
Analysis of prodrugs and associated species highly desirable
Hands-on familiarity running and maintaining industry-standard mass spectrometry instrumentation
Understanding of FDA and global regulatory requirements of study types assigned, as well as Testing Facility SOPs and Good Laboratory Practices (GLPs), as appropriate.
Highly motivated and results driven individual with a passion for working in a fast-paced and evolving organization
Outstanding communication, interpersonal, and partnering skills
Excellent cross-disciplinary skills in communicating scientific ideas to non-scientist stakeholders to foster collaboration and deliverable-based teamwork
Startup experience is highly valued. Ability to adjust rapidly to changing scientific priorities and technologies

The expected salary range for this role is $133,000-157,000, with the final offer based on experience, market data, and internal equity.

We are seeking an experienced scientist to take a key role in advancing preclinical discovery of its Glyph prodrug platform across a range of indications.

This listing is sourced directly from Seaport Therapeutics's careers page and normalized into a canonical job model.