Moderna
Senior Research Associate, Genome Sciences
Cambridge, Massachusetts, USA · Senior · Contract
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About the role
- As part of our vision, Moderna is committed to investing in R&D to further expand our impact on patients.
- The ideal candidate brings strong immune cell culture experience combined with demonstratable expertise and experience in immediate downstream molecular- and cell-based assays.
- Execute cell-based experiments to evaluate nucleic acid delivery, expression, durability, and related molecular and cellular outcomes.
Responsibilities
- Culture, maintain, and experimentally manipulate mammalian cell lines and primary human cells to support assay development and screening activities.
- Collaboratively develop and implement ddPCR workflows to quantify vector copy number and other DNA-based readouts relevant to genomic sciences studies.
- Partner closely across teams to generate high-quality samples and support PCR and potentially other molecular or sequencing workflows.
- Maintain accurate, detailed ELNs and records and help establish robust workflows, controls, and best practices.
- Demonstrated expertise in qPCR or ddPCR assay design, development, optimization, and data interpretation.
- Enthusiasm and a passion to deliver the greatest possible impact to people through mRNA medicines.
- Design, optimize, and execute qPCR assays for DNA and RNA quantification, including primer/probe design, assay qualification, controls, and standard curves.
- Candidates must already hold work authorization in US and be able to maintain that status without the need for future sponsorship.
- Demonstrated ability to independently design, execute, troubleshoot, and communicate experiments in a fast-paced research environment.
Requirements
- Strong mammalian cell culture experience, particularly with primary immune cell types such as T cells and PBMCs, with proven ability to generate reproducible, high-quality data.
- Experience with LNP and lipoplex transfection, electroporation, or other nucleic acid delivery workflows.
- Familiarity with PCR- and NGS-adjacent molecular characterization workflows.
- Familiarity with cellular engineering systems and tools for cell line generation and genomic medicines.
- Experience with flow cytometry and cell sorting.
Nice to have
- Here's What You'll Bring to the Table (Preferred Qualifications)
Skills
- Excellent organizational, documentation, and cross-functional communication skills.
Compensation
- The salary range for this role is $74,000.00 - $118,400.00.
Benefits
- Best-in-class healthcare coverage, plus voluntary benefit programs to support your unique needs
- A holistic approach to well-being, with access to fitness, mindfulness, and mental health support
- Family planning benefits, including fertility, adoption, and surrogacy support
- Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown
- Location-specific perks and extras
Company info
- The Role As part of our vision, Moderna is committed to investing in R&D to further expand our impact on patients.
- This position is not eligible for remote work. - At Moderna, we are focused on delivering on our mission by enabling talent to thrive.
- For this role, we are currently unable to offer immigration sponsorship.
- At Moderna, we are focused on delivering on our mission by enabling talent to thrive.
Visa & Work Authorization
- For this role, we are currently unable to offer immigration sponsorship.
This listing is sourced directly from Moderna's careers page and normalized into a canonical job model.