Moderna

Moderna

Senior Research Associate, Genome Sciences

Cambridge, Massachusetts, USA · Senior · Contract

No sponsorship$74k-$118kDetected 28 days ago
PCRqPCRFlow CytometryMolecular BiologyNGSCell CultureResearchCommunicationCollaboration

About the role

  • As part of our vision, Moderna is committed to investing in R&D to further expand our impact on patients.
  • The ideal candidate brings strong immune cell culture experience combined with demonstratable expertise and experience in immediate downstream molecular- and cell-based assays.
  • Execute cell-based experiments to evaluate nucleic acid delivery, expression, durability, and related molecular and cellular outcomes.

Responsibilities

  • Culture, maintain, and experimentally manipulate mammalian cell lines and primary human cells to support assay development and screening activities.
  • Collaboratively develop and implement ddPCR workflows to quantify vector copy number and other DNA-based readouts relevant to genomic sciences studies.
  • Partner closely across teams to generate high-quality samples and support PCR and potentially other molecular or sequencing workflows.
  • Maintain accurate, detailed ELNs and records and help establish robust workflows, controls, and best practices.
  • Demonstrated expertise in qPCR or ddPCR assay design, development, optimization, and data interpretation.
  • Enthusiasm and a passion to deliver the greatest possible impact to people through mRNA medicines.
  • Design, optimize, and execute qPCR assays for DNA and RNA quantification, including primer/probe design, assay qualification, controls, and standard curves.

Requirements

  • Strong mammalian cell culture experience, particularly with primary immune cell types such as T cells and PBMCs, with proven ability to generate reproducible, high-quality data.
  • Experience with LNP and lipoplex transfection, electroporation, or other nucleic acid delivery workflows.
  • Familiarity with PCR- and NGS-adjacent molecular characterization workflows.
  • Familiarity with cellular engineering systems and tools for cell line generation and genomic medicines.
  • Experience with flow cytometry and cell sorting.

Nice to have

  • Here's What You'll Bring to the Table (Preferred Qualifications)

Skills

  • Excellent organizational, documentation, and cross-functional communication skills.

Compensation

  • The salary range for this role is $74,000.00 - $118,400.00.

Company info

  • At Moderna, we are focused on delivering on our mission by enabling talent to thrive.

Visa & Work Authorization

  • For this role, we are currently unable to offer immigration sponsorship.

This listing is sourced directly from Moderna's careers page and normalized into a canonical job model.