Generate Biomedicines

Generate Biomedicines

Project Team Lead (PTL, cardio-renal-metabolic)

Somerville, MA · Director

Sponsorship not specified$177k-$260kDetected 142 days ago
Machine LearningLLMsA/B TestingRecruitingResearchLab ResearchExperimental DesignAnimal StudiesLeadershipCommunicationCollaboration

Stay score

odds of building a lasting career here

56Sponsors, lottery-bound
Cap-exempt (no lottery)0
Sponsors this role72
Entry-level history0
PERM / green-card track0
Lottery odds (Level IV)94
Fits your clock70

Sponsors, but it's cap-subject — you still face the weighted lottery (~61% per draw at Level IV). Good if you win; have a cap-exempt backup on your list.

Lottery odds assume a STEM candidate.

Personalize to your clock →

Employer immigration record

from this employer's Department of Labor filings

Files H-1B transfers

2 transfer filings in the last year, covering 2 workers. Median labor-condition decision: 7 days. An employer that already files transfers is one that can take over an existing H-1B.

Sourced from Department of Labor LCA, PERM and prevailing-wage disclosure data. Employer matching is by name, so figures may be split across an employer's legal entities. Absence of a filing means none appears in our copy of the data, not that none exists.

Community outcomes

No reports yet — be the first to help the next applicant.

About the role

  • This is a Director-level role with broad matrix leadership responsibilities and significant influence across research, platform, translational, and portfolio decisions.
  • This role is accountable for the overall success of assigned programs, including project-level decisions, go or no-go recommendations, and clear communication of program strategy, risks, and tradeoffs to senior leadership.
  • Be accountable for the progress of assigned programs, including overall scientific direction, team effectiveness, execution quality, and readiness for key stage-gate decisions.

Responsibilities

  • The PTL combines deep scientific judgment, strategic program leadership, and operational rigor to shape integrated research plans, drive execution, and ensure programs progress efficiently through key decision points.
  • Working closely with the Portfolio Lead, project managers, and functional leaders, the PTL will facilitate cross-functional discussions, make recommendations, and own final project decisions within the team structure.
  • The PTL will also represent programs in governance forums, shape portfolio strategy, and drive alignment across functions in ways that support broader company priorities.
  • Develop and maintain integrated program strategies and plans that align scientific objectives, timing, dependencies, resourcing, budgets, critical path activities, and decision points.
  • Facilitate team discussions, synthesize diverse inputs, make clear recommendations, and drive timely project team decisions and go or no-go recommendations.
  • Partner with the Portfolio Lead and senior functional leaders to shape portfolio strategy, refine program direction as data emerge, and ensure execution remains aligned with company priorities.
  • Drive execution across wet lab, computational, platform, and translational workstreams, ensuring scientific rigor, strong documentation, reproducibility, and high-quality data packages.
  • Develop program resource plans and budget assumptions, and partner with the Portfolio Lead and functional leaders on final resource and budget decisions.
  • Anticipate and resolve risks, gaps, and cross-functional dependencies to maintain program momentum in a fast-moving environment.
  • Set clear performance expectations for the core team and build a high-performing, collaborative team culture grounded in accountability, transparency, and urgency.

Requirements

  • Identify and advance therapeutic opportunities and target proposals by applying a strong understanding of biology, translational relevance, clinical context, and Generate's differentiated platform capabilities.

Nice to have

  • Experience working on protein therapeutics and related modalities in discovery or development settings, including peptides and conjugate-based approaches.
  • Experience with target selection and target validation, including assessment of biological rationale, tractability, translational relevance, and overall fit with portfolio strategy.
  • Understanding of translational strategy, including PK/PD considerations and the role of translational studies in guiding program decisions.
  • Familiarity with IND-enabling studies and early clinical development.
  • Who Will Love This Job:
  • A biomedical scienstist who loves hunting for novel targets and turning early scientific ideas into well-defined therapeutic opportunities.
  • A scientifically grounded leader who enjoys owning complex programs and making high-stakes decisions with incomplete information.
  • A person who enjoys connecting biology, platform capabilities, translational thinking, and portfolio priorities to move the most promising ideas forward.

Compensation

  • The base salary range provided reflects our current estimate of what we anticipate paying for this position.
  • Your actual base salary will be based on several factors, including job-related skills, experience, internal equity, relevant education or training, and market dynamics.
  • In addition, you will be eligible for an annual bonus, equity compensation, and a competitive benefits package.
  • Per Year Salary Range
  • $177,000 - $260,000 USD

Company info

  • Founded in 2018, we are advancing a growing pipeline of clinical and preclinical programs across multiple disease areas and protein modalities.
  • We bring diverse perspectives to a shared goal of delivering better medicines to patients in need, faster, guided by our values and leadership behaviors.

Visa & Work Authorization

  • al employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status
Apply directly at Generate Biomedicines →Create a free account for alerts like thisView Generate Biomedicines immigration profile

This listing is sourced directly from Generate Biomedicines's careers page and normalized into a canonical job model.