Xaira Therapeutics

Xaira Therapeutics

Director of Bioanalytical Sciences

South San Francisco, California, United States · Director

Sponsorship not specified$173k-$225kDetected 120 days ago
LLMsPharmacologyFDA RegulatoryFlow CytometryResearchExperimental DesignProtein AnalysisAnimal StudiesMentoring

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odds of building a lasting career here

56Sponsors, lottery-bound
Cap-exempt (no lottery)0
Sponsors this role72
Entry-level history0
PERM / green-card track0
Lottery odds (Level IV)94
Fits your clock70

Sponsors, but it's cap-subject — you still face the weighted lottery (~61% per draw at Level IV). Good if you win; have a cap-exempt backup on your list.

Lottery odds assume a STEM candidate.

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Employer immigration record

from this employer's Department of Labor filings

Files H-1B transfers

1 transfer filing in the last year, covering 1 worker. Median labor-condition decision: 7 days. An employer that already files transfers is one that can take over an existing H-1B.

Sourced from Department of Labor LCA, PERM and prevailing-wage disclosure data. Employer matching is by name, so figures may be split across an employer's legal entities. Absence of a filing means none appears in our copy of the data, not that none exists.

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About the role

  • About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development.
  • Xaira is headquartered in the San Francisco Bay Area, Seattle, and London.

Responsibilities

  • Lead the development, optimization, qualification, and validation of ligand-binding assays (e.g., ELISA, MSD, ECL) and flow cytometry-based methods for PK, PD, receptor occupancy, and target engagement to support both non-GLP and IND-enabling GLP studies.
  • Direct the design and interpretation of DMPK and bioanalytical studies, integrating PK/PD and exposure data to support candidate selection and translational dose projection.
  • Serve as the primary technical and relationship lead for CRO partnerships - selecting, onboarding, and managing external labs
  • Author and review bioanalytical sections of regulatory documents (IND, IB, study reports) and ensure methods meet GLP and current FDA/EMA/ICH M10 bioanalytical method validation guidance.
  • Collaborate cross-functionally with discovery biology, protein sciences, pharmacology, toxicology, clinical, and regulatory teams to align bioanalytical endpoints with program goals.
  • As pipeline evolves, build and manage a focused internal team.
  • Serve as the primary technical and relationship lead for CRO partnerships - selecting, onboarding, and managing external labs; reviewing protocols, validation plans, and data packages; and ensuring on-time, high-quality deliverables.
  • Xaira Therapeutics an equal-opportunity employer. We believe that our strength is in our differences. Our goal to build a diverse and inclusive team began on day one, and it will never end.
  • Our goal to build a diverse and inclusive team began on day one, and it will never end.

Requirements

  • More than 10 years of biotech/pharmaceutical industry experience in bioanalytical or DMPK development for biologics.
  • Deep expertise in bioanalytical method development, qualification, and validation for large molecules across human and preclinical species (NHP and rodent).
  • Demonstrated hands-on and strategic experience with PK, PD, and receptor occupancy assays, and with DMPK study design and interpretation.
  • Working knowledge of GLP and regulatory bioanalytical guidance (FDA, EMA, ICH M10).
  • Experience managing and mentoring staff scientists including in a matrixed environment.

Nice to have

  • Experience supporting IND filings and early clinical development for biologics.
  • Familiarity with platforms such as MSD/ECL, Gyrolab, Simoa, and multiparameter flow cytometry.
  • Experience integrating PK/PD modeling and translational data.
  • however, the base pay offered will vary depending on the market, job-related knowledge, skills and capabilities, and experience.
  • Xaira Therapeutics an equal-opportunity employer.
  • We believe that our strength is in our differences.
  • TO ALL RECRUITMENT AGENCIES: Xaira Therapeutics does not accept agency resumes.
  • Please do not forward resumes to our jobs alias or employees.

Skills

  • Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development.

Compensation

  • We offer a competitive compensation and benefits package, seeking to provide an open, flexible, and friendly work environment to empower employees and provide them with a platform to develop their long-term careers.
  • We offer a competitive package that includes base salary, bonus, and equity.
  • The base pay range for this position is expected to be $173,000 - $225,000 annually
  • however, the base pay offered will vary depending on the market, job-related knowledge, skills and capabilities, and experience.

Benefits

  • A Summary of Benefits is available for all applicants.
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This listing is sourced directly from Xaira Therapeutics's careers page and normalized into a canonical job model.