Twist Bioscience

Twist Bioscience

Sr Staff Mechanical Engineer

USA - Portland, OR · Staff+

Sponsorship not specifiedDetected 15 days ago
Agentic AISolidWorksAltiumSystems EngineeringRoboticsMechanical DesignElectrical EngineeringHardware DesignBioinformaticsCommunicationWritingTolerance Analysis

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odds of building a lasting career here

37Risky
Cap-exempt (no lottery)0
Sponsors this role80
Entry-level history0
PERM / green-card track0
Lottery odds40
Fits your clock70

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Employer immigration record

from this employer's Department of Labor filings

Files H-1B transfers

4 transfer filings in the last year, covering 4 workers. Median labor-condition decision: 7 days. An employer that already files transfers is one that can take over an existing H-1B.

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About the role

  • Based primarily on-site in Wilsonville, OR with partial remote flexibility, this role requires occasional travel to Twist in South San Francisco, CA and to vendor locations.
  • Just as children learn to both read and write, the next phase of development for the genomics revolution is the ability to write DNA.
  • Twist Bioscience Corporation is an Equal Opportunity Employer.

Responsibilities

  • Use SolidWorks to design multiple instruments that integrate liquid handling, consumable handling, imaging & robotics that meet or exceed System & Hardware requirements
  • Manage and use SolidWorks AI Agents to create new hardware designs leveraging parts & assemblies already in Twist's PDM environment
  • Work with other team members to develop and refine requirements
  • Perform tolerance analysis as needed
  • Support contract manufacturers and vendors as the Mechanical Technical Lead for your designs
  • Work with other team members to execute and support Factory and Site Acceptance Testing
  • Compile content and hold multiple design reviews as needed
  • Use SolidWorks to design & build test fixtures as needed to de-risk concept features or test sub-systems
  • Support Process Systems Engineers as needed during Concept Development and all other project phases
  • Provide system fluidics and electrical design documentation

Requirements

  • Extensive experience designing hardware for fluidics systems, including custom manifolds and integration of pumps, valves, sensors, regulators, etc.
  • Proven track record of collaborating with cross-functional teams-including engineers, scientists, and project managers-across the entire project lifecycle, from initial concept to post-release monitoring

Nice to have

  • Experience with Altium, Lucid, or other software tools that can be used to create wiring or plumbing diagrams

Skills

  • Strong experience with robotics/mechatronics and specifying electronic devices
  • Experience managing a CAD PDM system
  • Excellent communication and writing skills, and the ability to work in a fast-paced team environment
  • Very strong documentation skills
  • Proven ability to perform System Integration
  • Additional Bonus
  • Proficiency in 3DExperience
  • Experience with mechanical design for optical systems
  • In-depth knowledge and use of machine shop tools (band saws, Mill, drill press, sanders)
  • Experience performing electrical and electronics troubleshooting
  • Experience in specifying device control
  • Experience compiling and releasing QA documentation

Company info

  • At Twist Bioscience, we work in service of people who are changing the world for the better.
  • In fields such as health care, agriculture, industrial chemicals and data storage, our unique silicon-based DNA Synthesis Platform provides precision at a scale that is otherwise unavailable to our customers.
  • We are seeking a Senior Staff Mechanical Engineer to design, build, and test our next-generation automated wet-lab instruments.
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This listing is sourced directly from Twist Bioscience's careers page and normalized into a canonical job model.