Genentech

Genentech

Scientist 2, Biochemical and Cellular Pharmacology

South San Francisco

Sponsorship not specified$86k-$159kDetected 1 day ago
PythonData AnalysisExcelRoboticsPharmacologyFlow CytometryResearchProtein AnalysisProblem SolvingTime ManagementPublic Speaking

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odds of building a lasting career here

59Sponsors, lottery-bound
Cap-exempt (no lottery)0
Sponsors this role100
Entry-level history0
PERM / green-card track0
Lottery odds (Level III)83
Fits your clock70

Sponsors, but it's cap-subject — you still face the weighted lottery (~45% per draw at Level III). Good if you win; have a cap-exempt backup on your list.

Lottery odds assume a STEM candidate.

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About the role

  • Join Genentech's Biochemical and Cellular Pharmacology Department and help shape the future of cardio-metabolic therapeutics.

Responsibilities

  • Operating at the intersection of cutting-edge science and drug development, you will support the selection and characterization of therapeutic candidates across our pipeline.
  • In this role, you will develop, validate, and execute sophisticated biochemical and cell-based assays in heterologous and physiologically relevant systems to evaluate drugs in cardiovascular, renal and metabolic areas.
  • You will support projects from initial lead finding through optimization, conducting detailed mechanistic studies on complex receptor signaling pathways and protein interactions.
  • Ultimately, your scientific insights will help define target candidate profiles and shape the screening cascades that deliver our next-generation therapeutics.
  • Pioneer novel assay platforms that interrogate complex receptor pharmacology and mechanism of action, showing scientific curiosity and reviewing literature to drive your initiatives
  • Drive automation and efficiency using laboratory robotics (Bravo, Tecan, Echo…) to streamline workflows and accelerate timelines
  • Collaborate across multidisciplinary teams in a fast-paced environment, generate high-quality presentations, and communicate findings to stakeholders

Requirements

  • Bachelor's degree and/or Master's degree in Cell Biology, Pharmacology, Biochemistry, or related field
  • 5+ years of hands-on research experience in fast-paced pharma or biotech environments
  • Expert-level proficiency with culture of mammalian cells, primary cells, and stable cell line generation
  • Hands-on experience with a variety of microplate-format biochemical and cellular assays (e.g., HTRF, AlphaScreen, or luminescence-based readouts)

Nice to have

  • Expertise in the cardiovascular, renal, or metabolic disease field
  • Experience with flow cytometry, ELISA assays, or high-content image analysis
  • Experience with lab automation and high-throughput screening
  • Proficiency with data analysis software and visualization tools (GraphPad Prism, Genedata, Excel, Python, R)

Compensation

  • The expected salary range for this position based on the primary location of South San Francisco, CA is $85,500 to $158,700.

Company info

  • We are seeking a creative, motivated scientist to drive the discovery and characterization of innovative drug candidates that could transform patient outcomes.

Equal opportunity

  • equal opportunity employer.
  • If you have a disability and need an accommodation in relation to the online

This listing is sourced directly from Genentech's careers page and normalized into a canonical job model.