Twist Bioscience
Sr Scientist, Antibody Discovery
USA - Quincy, MA · Senior
Sponsorship not specified$131k-$143kDetected 41 days ago
Project ManagementBioinformaticsFlow CytometryLab ResearchMass SpectrometryProtein AnalysisAnimal StudiesCommunicationProblem SolvingOrganizational Skills
About the role
- It is anticipated that the role would involve an 80/20 split of analysis vs wet lab time.
- About Twist Bioscience Twist Bioscience synthesizes genes from scratch, known as "writing" DNA.
Responsibilities
- As an individual contributor Senior Scientist, you will support members of multiple scientific teams as a Project Lead, but will not directly manage team members.
- Serve as an end-to-end technical lead for a variety of in vivo antibody discovery programs and contract services, contributing to scientific planning and feasibility review during project scoping.
- Actively participate in team meetings, clearly articulating needs, concerns, and proposed solutions to drive efficient collaboration.
- This is an individual contributor role that provides support for bioanalytical characterization for a variety of assays critical for characterizing therapeutic antibody candidates.
Requirements
- PhD in a related technical field with 5+ years of experience in biopharmaceutical analytical development or master's in a. related technical field with 10+ years of experience
- Expert knowledge of antibody biologics characterization assays: extensive hands-on experience required in Carterra SPR, Octet BLI, ELISA, flow cytometry, and antibody developability characterization.
- Proven ability to assess, interpret, and present complex scientific data effectively and with a high level of integrity and ethics.
- Just as children learn to both read and write, the next phase of development for the genomics revolution is the ability to write DNA.
Nice to have
- Strong knowledge of antibody and biologics characterization is required.
- Previous experience with Carterra SPR systems, Octet BLI, and/or developability assays (HPLC and high throughput plate-based) is required.
- Further direct experience is expected with ELISA, SDS-PAGE, protein quantification, and endotoxin assays.
- Experience in high-throughput assays (1,000s of samples) is preferred.
- Ability to troubleshoot scientific processes, make sound scientific decisions on tight timelines, and accurately analyze and report data with utmost attention to detail.
- Ability to work simultaneously on multiple workflows, prioritizing effectively.
- Effectively communicate project updates, risks, and progress to the manager and cross-functional team members in a timely and professional manner.
- The base cash compensation for this Massachusetts-based role is below.
Compensation
- The base cash compensation for this Massachusetts-based role is below.
Company info
- Review, critically analyze, and present data to customers for a variety of concurrent antibody discovery programs.
- Work closely with the Project Management team to communicate timelines and deliverables to internal and external stakeholders and customers.
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