Novartis Group Companies

Novartis Group Companies

Senior Scientist, Protein Production

San Diego · Senior

Sponsorship not specifiedDetected 12 days ago
ExpressMachine LearningData AnalysisClinical TrialsClinical ResearchCRISPRMolecular BiologyCell CultureResearchMass SpectrometryProtein AnalysisCommunicationCollaborationProblem SolvingCritical Thinking

About the role

  • Come help us discover innovative therapeutic breakthroughs for patients!
  • We are seeking a passionate, curious, and collaborative protein scientist to join our Protein Sciences group, an interdisciplinary team that has expertise in protein chemistry, enzymology, biophysics, NMR, X-ray crystallography, and electron microscopy.
  • As a Protein Scientist, you will focus primarily on the production of proteins to enable structure-guided drug discovery for multiple disease areas.

Responsibilities

  • Develop and execute protocols to generate high-quality protein reagents for small molecule screening, hit validation, and structural biology studies of protein-small molecule complexes.
  • Design protein constructs based on literature and AI-based structure prediction tools.
  • Collaborate with colleagues to characterize protein-protein and protein-ligand interactions using biophysical and structural biology techniques.
  • Apply critical thinking to troubleshoot experiments and design new approaches.
  • Maintain a high level of professional expertise through familiarity with scientific literature and accurate and detailed record keeping.
  • Proven in-depth knowledge with hands-on experience in recombinant protein construct design and expression, including insect cell and mammalian expression systems.
  • We strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Requirements

  • BS/MS degree in biochemistry, life sciences, molecular biology or related field with at least 5+ years of relevant research laboratory experience.
  • Proficiency in different protein purification techniques such as affinity, ion exchange, and gel filtration chromatography using FPLC or HPLC systems.
  • Excellent communication skills, both oral and written, and ability to work effectively in a matrix team environment.
  • Experience in protein crystallography, bio-NMR, or cryo-EM, either directly or working closely with others.
  • Experience in biophysical methods to characterize protein-protein or protein-ligand interactions.

Compensation

  • $93,800.00 - $174,200.00
  • The salary for this position is expected to range between $93,800 and $174,200 per year for Senior Scientist I, and $98,700 and $183,300 for Senior Scientist II.
  • The final salary offered is determined based on factors like, but not limited to, relevant skills and experience, and upon joining Novartis will be reviewed periodically.
  • Novartis may change the published salary range based on company and market factors.

Benefits

  • Your compensation will include a performance-based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards.
  • US-based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a variety of other benefits.
  • In addition, employees are eligible for a generous time off package including vacation, personal days, holidays and other leaves.
  • To learn more about the culture, rewards and benefits we offer our people click here.

Company info

  • Work both independently and collaboratively as part of multidisciplinary teams.

Equal opportunity

  • The Novartis Group of Companies are Equal Opportunity Employers.
  • Accessibility and reasonable accommodations
  • The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities.
  • Please include the job requisition number in your message.
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