Biogen
Director, Biotherapeutics Discovery
San Francisco, CA · Director
Sponsorship not specified$204k-$281kDetected 8 days ago
Machine LearningPharmacologyMolecular BiologyResearchLeadershipCommunicationCollaboration
About the role
- At Biogen, we are committed to discovering, developing, and delivering innovative therapies for people living with serious neurological and immunological diseases.
- In this role, you will lead biologics efforts for Biotherapeutics Discovery at Biogen's West Coast Hub in South San Francisco.
- You will drive cross-functional research and portfolio programs, shape the strategy around tomorrow's way of discovering biological drugs, and advance discovery innovation in close partnership with colleagues across the broader Research organization including key teams in Cambridge, MA.
Responsibilities
- Lead and develop a high-performing team while advancing biologics technologies and platform innovation aligned with portfolio priorities
- In strong partnership with the Cambridge, MA team, support antibody discovery, engineering, optimization, and candidate selection strategies across discovery programs
- Contribute to molecular design strategies, including multi-specifics, novel formats, affinity tuning, epitope targeting, and developability assessments
- Partner across functions, including protein engineering, computational design, pharmacology, translational sciences, Immunology, and Neurology, to initiate and shape discovery campaigns
- Guide modality and candidate selection based on target biology, mechanism of action, and translational considerations, and support early target assessments that test key biological hypotheses
Requirements
- You are a strategic and collaborative scientific leader with deep expertise in biologics discovery and antibody engineering.
- 12+ years of industry experience in biologics drug discovery, including leadership of antibody discovery and optimization programs
- Proven success advancing molecules from discovery through candidate nomination
- Experience across biologics modalities, including bispecifics, fusion proteins, and conjugates
- Strong track record of cross-functional partnership, including collaboration with disease biology teams
- Excellent communication and leadership skills, with the ability to influence scientific direction across teams and sites
- Ph.D. in biochemistry, immunology, molecular biology, or a related scientific discipline
- Deep expertise in antibody engineering, molecular design, and biologics discovery workflows
- Demonstrated experience leading and developing scientific teams
- Additional Qualifications
- Familiarity with computational design or AI/ML applications in biologics discovery
Nice to have
- Experience in translational immunology and a strong understanding of immunology disease biology
- Experience partnering with Immunology or Neurology research teams
- Background in early target assessment and discovery campaign initiation
- Experience identifying and sourcing external innovation through collaborations with CROs, biotech companies, or academic groups
- Job Level: Management
Compensation
- Tuition reimbursement of up to $10,000 per calendar year
Benefits
- Medical, Dental, Vision, & Life insurances
- Fitness & Wellness programs including a fitness reimbursement
- Paid Maternity and Parental Leave benefit
- Build an inclusive culture of innovation, accountability, and continuous learning
- Short- and Long-Term Disability insurance
- A minimum of 15 days of paid vacation and an additional end-of-year shutdown time off (Dec 26-Dec 31)
- Employee stock purchase plan
- Base salary offered is determined through an analytical approach utilizing a combination of factors including, but not limited to, relevant skills & experience, job location, and internal equity.
Company info
- Up to 12 company paid holidays + 3 paid days off for Personal Significance
- 401(k) program participation with company matched contributions
- We are a global team with a commitment to excellence, and a pioneering spirit.
- As a mid-sized biotechnology company, we provide the stability and resources of a well-established business while fostering an environment where individual contributions make a significant impact.
This listing is sourced directly from Biogen's careers page and normalized into a canonical job model.