Eikontherapeutics

Director, High-Throughput Biology

Millbrae, CA · Director

Sponsorship not specified$213k-$257kDetected 2 days ago

Machine LearningData AnalysisStatisticsRoboticsMicroscopyLeadershipMentoring

About the role

Eikon Therapeutics is a new biopharmaceutical company employing revolutionary technology at the intersection of chemistry, engineering, computation, and biology to discover novel treatments for life-threatening diseases.
Position The Director, High-Throughput Biology (HTB) is responsible for the strategy, performance, and evolution of Eikon's high-throughput screening and discovery platforms.
You are comfortable operating at both the strategic and technical level, balancing organizational leadership with hands-on scientific engagement where needed.

Partner cross-functionally at the assay-to-screening interface to align assay readiness, screening feasibility, platform capabilities, and project priorities.
Lead high-throughput screening strategy and execution, partnering with HTB scientists and program leadership to drive prioritization, ensure feasibility, and enable data-driven decisions.
Optimize team resourcing and representation to support screening design, execution, analysis, and program engagement across scientists and SRAs.
Lead an integrated platform organization that aligns biology, automation, and data analytics into a cohesive screening engine, including workflows, robotics integration, quality control, reporting, and data practices.
Build, develop, and retain a high-performing team through clear accountability, coaching, and development of technical and cross-functional capability.
Provide hands-on technical leadership by shaping assay strategy, screening design, analytical methods, and data or automation tooling where needed.

PhD in Biological Sciences, Computational Sciences, or a related discipline with 10+ years of experience in high-throughput or high-content screening environments.
Demonstrated expertise with automated screening platforms, including 384- and/or 1536-well formats.
Experience screening compound libraries larger than 100k.
Experience with microscopy-based or imaging-enabled screening platforms.
Experience with genetic screens or systems biology approaches.
Strong expertise in statistical analysis and large-scale dataset quality control, with proficiency in Python.
Proficiency with compound databases, LIMS, and enterprise data systems.
Proven cross-functional leadership across biology, chemistry, engineering, and data teams.
Experience advancing drug discovery programs from hit identification through lead optimization.
Experience building or contributing to scalable data processing pipelines.
Strong computational science capability and familiarity with machine learning or artificial intelligence applications in phenotypic or multiparametric screening are preferred.
Demonstrated ability to build hybrid biology and computational teams is preferred.

Experience with single-molecule imaging technology is preferred.
Experience with novel technologies or assay development for drug discovery is preferred.

At Eikon, employee compensation also includes bonus and equity compensation, in addition to several generous benefit programs, including:

Set the vision and operating model for HTB, defining strategy, success metrics, and standards that ensure sustainable, reliable, high-quality screening data delivery across the portfolio.
Medical (premiums covered by Eikon at 95%), dental and vision insurance (premiums covered by Eikon at 100%)
Mental health and wellness benefits
Weeklong summer and winter holiday shutdowns
Generous paid time off and holiday policies
Enhanced parental leave benefit

This listing is sourced directly from Eikontherapeutics's careers page and normalized into a canonical job model.