Elanco
Principal Research Scientist - Medicinal Chemist
Indianapolis, IN · Principal
Sponsorship not specifiedDetected 29 days ago
Machine LearningLead GenerationIntellectual PropertyPharmacologyResearchAnimal StudiesMentoring
About the role
- Principal Research Scientist - Medicinal Chemist
- Partnering with a global, cross-functional team of scientists, you will leverage cutting-edge technologies like AI/ML and DNA-Encoded Libraries to solve complex chemical challenges.
- This is an exciting opportunity to make a significant impact on our discovery portfolio and help shape the future of our growing research team in Indianapolis.
Responsibilities
- Guide the design and optimization of novel small molecules by applying advanced synthetic strategies and integrating biological, pharmacological, and ADME/PK data to manage Structure-Activity Relationship (SAR) campaigns.
- Serve as a key medicinal chemistry figure on multidisciplinary project teams, collaborating with partners in Biology, Pharmacology, DMPK, Toxicology, and Computational Sciences to strategically advance discovery programs.
- Manage and coordinate synthetic chemistry efforts with external Contract Research Organizations (CROs) and internal partners, ensuring the efficient execution of project goals and timelines.
- Leverage cutting-edge drug discovery technologies, including DNA-Encoded Libraries (DEL), computational chemistry, and AI/ML-enabled tools, to accelerate hit identification and lead optimization.
- Elanco may use automated tools, including AI, to support parts of our recruitment process, such as reviewing applications against job‑related criteria and/or transferrable skills.
Requirements
- What You Need to Succeed (minimum qualifications):
Nice to have
- A strong track record of advancing small-molecule discovery programs toward preclinical development, evidenced by significant patent and/or publication contributions.
Skills
- What will give you a strong candidate profile (preferred qualifications):
- Postdoctoral experience.
- Prior research experience in the animal health industry.
- Expertise in peptide chemistry, macrocycles, or related drug modalities.
Compensation
- Annual bonus offering
Benefits
- Two weeklong shutdowns (mid-summer and year-end) in the US (in addition to PTO)
- 8-week parental leave
- Annual bonus offering
- Flexible work arrangements
- Education: PhD in Medicinal Chemistry, Organic Chemistry, or a related scientific discipline.
Company info
- At Elanco we are dedicated to building a diverse and inclusive work environment.
This listing is sourced directly from Elanco's careers page and normalized into a canonical job model.